产品详情 |
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Antigenic Specificity | CDC42 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CDC42 polyclonal antibody. The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudoge |
Immunogen | cell division cycle 42 (GTP binding protein, 25kDa) |
Other Names | n/a |
Gene, Accession # | Gene ID: 998, UniProt: P60953 |
Catalog # | FNab01530 |
Price | |
Order / More Info | CDC42 Antibody from FINETEST |
Product Specific References | n/a |
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