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Antigenic Specificity | CD14, Mouse |
Clone | Sa14-2 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.5 mg |
Concentration | 101 µg/ml |
Applications | FC, functional studies, IF, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody Sa14-2 reacts with the mouse monocyte marker CD14, a 53 kDa glycoprotein. CD14 is a glycophosphatidylinositol-linked protein, which is part of the LPS receptor complex. CD14 binds lipopolysaccharide (LPS) and as such, acts as a pattern recognition receptor (PRR). CD14 has also been suggested to mediate phagocytosis of bacteria an apoptotic cells. CD14 is involved in the endotoxin mediated release of Tumor Necrosis Factor-alpha by monocytic cells. CD14 is present on most monocytic and macrophage like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is present in low density on a subpopulation of granulocytes and activated or transformed B-cells. |
Immunogen | CD14 transfectant |
Other Names | Monocyte differentiation antigen CD14 |
Gene, Accession # | n/a |
Catalog # | HM1060-FS |
Price | |
Order / More Info | CD14, Mouse Antibody from HYCULT BIOTECH |
Product Specific References | n/a |
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