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| Product Name | PYCRL, 1-274aa, Human, His tag, E Coli |
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| Description | MW: 31 kDa (297aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. PYCRL belongs to the pyrroline-5-carboxylate reductase family and functions as a homodecamer. It may play a critical role in proline bio-synthesis. Proline functions as a non-enzymatic antioxidant to minimize damage caused by reactive oxygen species (ROS) in microorganisms, animals and plants. In the last step of proline biosynthesis, PYCRL catalyzes the reduction of aldehyde dehydrogenase 4A1 (ALDH4A1) to proline using NAD (P) |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Pyrroline-5-carboxylate reductase 3; P5C reductase 3; P5CR 3; pyrroline-5-carboxylate reductase 3] |
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| Gene, Accession, CAS # | PYCRL, Gene ID: 65263, Accession: AAH07993 |
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| Catalog # | MBS205021 |
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| Order / More Info | PYCRL, 1-274aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Nocek B., et al. (2005) J Mol Biol. 354:91-106.; Krishnan N., et al. (2008) Free Radic Biol Med. 44: 671-681. |
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