| 产品名称 |
PDIA6, Recombinant, Human, aa20-440, His-Tag(Protein disulfide-isomerase A6 , ERP5, P5, TXNDC7) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | PDIA6, Recombinant, Human, aa20-440, His-Tag(Protein disulfide-isomerase A6 , ERP5, P5, TXNDC7) |
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| Description | Purity ~90% (SDS-PAGE). PDIA6 is a member of the protein disulfide isomerase (PDI). PDI is an enzyme in the endoplasmic reticulum in eukaryotes or periplasmic space of prokaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. PDIA6 function as a chaperone that inhibits aggregation of misfolded proteins. It plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin Source: Recombinant protein corresponding to aa20-440 from human PDIA6, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~48.5kD (442aa) Specifc Activity: >20 A650/cm/min/mg. Enzymatic activity was confirmed by measuring the aggregation of insulin in the presence of DTT. Activity Assay 1. Prepare a 180ul assay buffer into a suitable container: The concentrations are 0.67mM DTT, insulin 5.3mg, 1.2mM EDTA 2. Dilute insulin 8mg/ml in 3mM EDTA, pH 7.0, and incubate diluted insulin for 5 minutes at 37°C. 3. Dilute PDI |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_005733 |
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| Catalog # | 351419 |
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| Order / More Info | PDIA6, Recombinant, Human, aa20-440, His-Tag(Protein disulfide-isomerase A6 , ERP5, P5, TXNDC7) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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