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| Antigenic Specificity | p53 |
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| Clone | PAb240 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat, cow, dog, human, monkey, chicken, Chinese hamster, Syrian hamster |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 50ul |
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| Concentration | 1mg/ml |
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| Applications | Flow cyt, ICC/IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse anti p53 [PAb240]: Fluorescein. This antibody recognises cellular tumour antigen p53, a 50kDa transcription factor and major tumour suppressor that plays a major role in regulating cellular responses to DNA damage and other genomic aberrations. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. The Pab240 antibody recognizes an epitope between amino acids 156-214 on murine p53. |
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| Immunogen | Purified p53-b-galactosidase fusion protein containing p53 sequence from amino acids 14-389 |
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| Other Names | Antigen NY-CO-13; Cellular tumor antigen p53; FLJ92943; LFS1; P53; p53 antigen; p53 transformation suppressor; p53 tumor suppressor; Phosphoprotein p53; TP53; transformation-related protein 53; TRP53; tumor protein p53; Tumor suppressor p53 |
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| Gene, Accession # | n/a |
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| Catalog # | IQ624FITC |
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| Price | |
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| Order / More Info | p53 Antibody from IMMUQUEST LTD. |
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| Product Specific References | Gannon JV, et al. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J. 1990.9(5):1595-602. PMID:1691710 http://www.ncbi.nlm.nih.gov/pubmed/1691710 |
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