| 产品详情 |
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| Antigenic Specificity | PP2A alpha (methyl L309) |
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| Clone | 2A10 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat, human.predicted to work with: Saccharomyces cerevisiae |
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| Isotype | IgG1 |
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| Format | peroxidase (HRP) conjugate |
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| Size | 50ul |
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| Concentration | 1mg/ml |
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| Applications | IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-PP2A alpha (methyl L309) [2A10]: Horseradish Peroxidase (HRP). This antibody specifically recognises the C-terminally methylated form of PP2A C subunit. |
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| Immunogen | A KLH-coupled peptide with the sequence: KLH-C- A-RRTPDYFL-OMe. The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast |
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| Other Names | PP2A alpha, PP2A C, PP2A-alpha, PP2AA_HUMAN, PP2Ac, PP2CA, PPP2CA, Protein phosphatase 2, catalytic subunit, alpha isoform, Replication protein C |
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| Gene, Accession # | n/a |
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| Catalog # | IQ556HRP |
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| Price | |
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| Order / More Info | PP2A alpha (methyl L309) Antibody from IMMUQUEST LTD. |
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| Product Specific References | Benziane B et al. Activation of AMP-activated Protein Kinase Stimulates Na ,K -ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB PUBMED Li T et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human PUBMED Finnegan S et al. A stress survival response in retinal cells mediated through inhibition of the serine / threonine phosphatase PP2A. Eur J Neurosci : (2010). WB ; Mouse PUBMED Hombauer H et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5:e155 (2007) PUBMED Sontag E et al. Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. J Neuropathol Exp Neurol 63:1080-91 (2004) PUBMED Sontag E et al. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. J Neuropathol Exp Neurol 63:287-301 (2004) PUBMED Fellner T et al. A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17:2138-50 (2003) PUBMED |
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