| 产品详情 |
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| Antigenic Specificity | RNA polymerase II CTD repeat YSPTSPS (phospho S5) |
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| Clone | 4H8 |
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| Host Species | Mouse |
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| Reactive Species | mouse, human, Saccharomyces cerevisiae, Arabidopsis thaliana, Caenorhabditis elegans, fruit fly (Drosophila melanogaster), Schizosaccharomyces pombe, African green monkey |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | 50ul |
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| Concentration | 0.8mg/ml |
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| Applications | Flow Cyt, ICC/IF, ChIP, ChIP/Chip, WB, ELISA, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) [4H8] - ChIP Grade. Recognises the C-terminal repeat of the largest subunit of RNA polymerase II. It recognises both unphosphorylated and phosphorylated forms. |
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| Immunogen | Synthetic peptide: YSPTSpPS (Human). The sequence is repeated multiple times in the C-terminal domain of RNA polymerase II |
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| Other Names | DNA directed RNA polymerase II A, DNA-directed RNA polymerase II largest subunit; DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit, Polr2a, RNA pol II CTD, RNApolymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RPB1, RPB1_HUMAN |
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| Gene, Accession # | n/a |
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| Catalog # | IQ287 |
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| Price | |
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| Order / More Info | RNA polymerase II CTD repeat YSPTSPS (phospho S5) Antibody from IMMUQUEST LTD. |
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| Product Specific References | The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase Yart A et al. Cell Biol. 2005 Jun;25(12):5052-60 ChIP ; HumanPMID: 15923622 Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation Kristjuhan A, Wittschieben BO, Walker J, Roberts D, Cairns BR, Svejstrup JQ. ( Proc Natl Acad Sci U S A,2003) PUBMED Keren-Shaul H et al. Pre-mRNA splicing is a determinant of nucleosome organization. PLoS One 8:e53506 (2013). WB, ChIP ; Human PUBMED Schmucker AC et al. Distal Interleukin-1AY (IL-1AY) Response Element of Human Matrix Metalloproteinase-13 (MMP-13) Binds Activator Protein 1 (AP-1) Transcription Factors and Regulates Gene Expression. J Biol Chem 287:1189-97 (2012). ChIP ; Human PUBMED Davidson L et al. Co-transcriptional degradation of aberrant pre-mRNA by Xrn2. EMBO J 31:2566-78 (2012). ChIP PUBMED Harrigan JA et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J Cell Biol 193:97-108 (2011). ICC/IF ; Human PUBMED Chen X et al. Sequential changes at differentiation gene promoters as they become active in a stem cell lineage. Development 138:2441-50 (2011) PUBMED |
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