产品名称 Ferulic Acid ethyl ester from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H7774
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameFerulic Acid ethyl ester
DescriptionPurity >98%. Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis ). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid ethyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid ethyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 66.7 µM for ferulic acid ethyl ester vs. 44.6 µM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). However, ferulic acid ethyl ester increases the expression of heme oxygenase-1, Hsp70, and Hsp72, providing neuroprotection against amyloid Beta-peptide. Moreover, ferulic acid ethyl ester (25 µM) completely prevents cytotoxicity induced by ultraviolet B irradiation of normal human epidermal melanocytes, again associated with an induced expression of heme oxygenase-1 and Hsp70.
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Other Names3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid, ethyl ester, BBR 3222, NSC 14879
Gene, Accession, CAS #CAS: 4046-02-0
Catalog #LS-H7774
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Order / More InfoFerulic Acid ethyl ester from LIFESPAN BIOSCIENCES INC.
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