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| Product Name | DKK1, 32-266aa, Human His tag, E Coli (Denatured) |
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| Description | MW: 28.2 kDa (258aa). Purity >90% by SDS-PAGE. Dickkopf-related protein 1, also known as DKK1, antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, D |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Dickkopf-related protein 1; Dickkopf-related protein 1; DKK-1; SK] |
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| Gene, Accession, CAS # | DKK1, Gene ID: 22943, Accession: NP_036374 |
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| Catalog # | MBS205352 |
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| Order / More Info | DKK1, 32-266aa, Human His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Ahn V.E., et al. (2011) Dev. Cell. 21:862-873; Haniu M., et al. (2011) Protein Sci. 20:1802-1813; |
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