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| Product Name | DKK2, 34-259aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 27.6 kDa (250aa). Purity >90% by SDS-PAGE. Dickkopf-related protein 2, also known as DKK2, belongs to the dickkopf family. DKK2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenes |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Dickkopf-related protein 2; DKK-2] |
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| Gene, Accession, CAS # | DKK2, Gene ID: 27123, Accession: NP_055236 |
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| Catalog # | MBS204569 |
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| Order / More Info | DKK2, 34-259aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Krupnik V.E., et al. (1999) Gene. 238:301-313; Clark H.F., et al. (2003) Genome Res. 13:2265-2270 |
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