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| Product Name | ARPP19, 1-112aa, Human, His tag, E Coli |
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| Description | MW: 14.7kDa (135aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. cAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GA |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by BCA assay) |
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| Applications | SDS-PAGE |
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| Other Names | [cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19; ARPP-16; ARPP-19; ARPP16; ENSAL] |
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| Gene, Accession, CAS # | ARPP19, Gene ID: 10776, Accession: NP_006619 |
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| Catalog # | MBS204876 |
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| Order / More Info | ARPP19, 1-112aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Gharbi-Ayachi A., et al. (2010) Science. 330:1673-1677; Choudhary C., et al. (2009) Science. 325:834-840 |
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