| 产品详情 |
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| Product Name | Fidaxomycin |
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| Description | Purity >95%. Fidaxomycin is a natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria (IC50 s = 0.4 and 6 µM, respectively). It has potent antibacterial activity against most Gram-positive bacteria and effectively targets the Gram-positive C. difficile (MIC = 12 ng/ml). Orally administered fidaxomycin exhibits minimal systemic bioavailability resulting in maximal gastrointestinal tract distribution. Fidaxomycin is effective in clearing C. difficile infections while sparing Gram-negative bacteria in the gut. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyet, Clostomicin B1, Lipiarmycin, Difimicin, OPT-80, PAR-101, Tiacumicin B |
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| Gene, Accession, CAS # | CAS: 873857-62-6 |
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| Catalog # | LS-H7788 |
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| Order / More Info | Fidaxomycin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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