| 产品详情 |
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| Product Name | IDE2 |
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| Description | Purity >98%. IDE2 is a small molecule capable of inducing definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50 = 223 nM in vitro ) by activating the TGF-Beta signaling pathway. IDE2-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation. Furthermore, when treated with either indolactam V or a standard regimen of the growth factor FGF-10, retinoic acid, and hedgehog inhibitors, IDE2-induced endodermal cells can form Pdx1-expressing pancreatic progenitors. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(2-cyclopentylidenehydrazide)-heptanedioic acid |
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| Gene, Accession, CAS # | CAS: 1136466-93-7 |
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| Catalog # | LS-H8174 |
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| Order / More Info | IDE2 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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