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| Product Name | Human IL5RA / CD125 Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE and HPLC, MW: 53-56 kDa (SDS-PAGE). Interleukin-5 Receptor Alpha (IL-5RA), also known as CD125, belongs to the Type 5 subfamily in the type I cytokine receptor family. It is composed of a ligand-specific alpha subunit and a signal-transducing beta subunit shared by the receptors for IL-3 and GM-CSF. IL-5RA is mainly expressed on eosinophils and basophils, and plays important roles in the immunobiology of these cell types. It is reported that when stimulated by IL-5, eosinophils down-regulate surface IL-5RA expression to attenuate their IL-5 responsiveness. Elevated IL-5 production may induce immune cell infiltration which leads to allergic inflammation. IL-5RA has also been reported to promote the differentiation of basophils and B cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL5RA, CD125, CD125 antigen, CDw125, HSIL5R3, IL-5R-alpha, Interleukin 5 receptor type 3, Interleukin 5 receptor, alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5RA, IL5R |
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| Gene, Accession, CAS # | IL5RA, Gene ID: 3568 |
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| Catalog # | LS-G27198 |
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| Price | |
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| Order / More Info | Human IL5RA / CD125 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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