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| Product Name | HAND2, Recombinant, Human, aa1-180, GST-Tag (Heart- and Neural Crest Derivatives-expressed Protein 2) |
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| Description | Purity ~90% (SDS-PAGE). Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. Source: Recombinant protein corresponding to aa1-180 from human HAND2, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~47.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Class A basic helix-loop-helix protein 26 |
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| Gene, Accession, CAS # | SwissProt: P61296 |
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| Catalog # | 373585 |
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| Order / More Info | HAND2, Recombinant, Human, aa1-180, GST-Tag (Heart- and Neural Crest Derivatives-expressed Protein 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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