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| Product Name | AXL, BioAssay™ ELISA Kit (Mouse) (Tyrosine-Protein Kinase Receptor UFO) |
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| Description | Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene, which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants. Sample Type: Cell culture supernate |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 26362, SwissProt: Q00993 |
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| Catalog # | 352715 |
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| Order / More Info | AXL, BioAssay™ ELISA Kit (Mouse) (Tyrosine-Protein Kinase Receptor UFO) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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