| 产品详情 |
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| Product Name | Mouse PDGF-AA Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE, MW: 29.0 kDa. Platelet Derived Growth Factor AA comes as a dimer having a 126/252 amino acid chain. Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by interleukin 1 (IL-1), interleukin 6 (IL-6), tumor necrosis factor alpha (TNFa), transforming growth factor beta (TGF-β), and epidermal growth factor (EGF) signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PDGFA, PDGF-A, PDGF A-chain, PDGF subunit A, PDGF-1, PDGF1 |
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| Gene, Accession, CAS # | PDGFA, Gene ID: 5154 |
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| Catalog # | LS-G23731 |
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| Order / More Info | Mouse PDGF-AA Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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