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| Product Name | Insulin-Like Growth Factor I, Recombinant, Human |
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| Description | Purity: ~98% (SDS PAGE/HPLC). Insulinlike Growth Factor I, is a secreted mitogenic polypeptide and member of the insulin gene family, produced primarily by the liver, which effects a wide range of cells and plays a key role in cell proliferation and growth, inhibition of apoptosis, and is linked with tumor cell growth. IGFI signals through binding to the type 1 insulinlike growth factor receptor (IGF1R) and also to the insulin receptor (IR), resulting in the activation of the AKT signalling pathway. IGFI production is stimulated by growth hormone (GH). and can be hindered by GH insensitivity, deficiency in GH receptors or a malfunction in the post GH receptor signalling pathway. Source: Recombinant corresponding to human IGF-I expressed in E.coli. Molecular Weight: ~7.6kD Activity: The ED50 was determined by a cell proliferation assay using FDCP1 cells is 5 x 105 units/mg. Endotoxin: <1EU/ug Applications: Suitable for use in Functio |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Insulin-Like Growth Factor I, Recombinant, Human (IGF1, IGF I, IGF-I, IBP1, Mechano Growth Factor, MGF, Somatomedia C, Somatomedin C) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I7661-02D |
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| Order / More Info | Insulin-Like Growth Factor I, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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