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| Product Name | Insulin-Like Growth Factor I, Recombinant, Rat (IGF1, Somatomedin C) |
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| Description | Purity ≥97%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Insulin-like growth factor I is the dominant effector of growth hormone and is structurally homologous to proinsulin. Rat IGFI is synthesized as four precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. The 7.6kD mature IGFI is identical between isoforms and is generated by proteolytic removal of the N- and C-terminal regions. Mature rat IGFI shares 96% and 99% aa sequence identity with human and mouse IGFI, respectively, and exhibits cross-species activity. It shares 61% aa sequence identity with mature rat IGFII. Circulating IGFI is produced by hepatocytes, while local IGFI is produced by many other tissues in which it has paracrine effects. IGFI induces the proliferation, migration and differentiation of a wide variety of cell types during development and postnatally. IGFI regulates glucose and fatty acid metabol |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAA41386 |
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| Catalog # | I7661-09K |
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| Order / More Info | Insulin-Like Growth Factor I, Recombinant, Rat (IGF1, Somatomedin C) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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