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| Product Name | PSMB10, 40-273aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl. PSMB10 is a member of the proteasome B-type family, also known as the T1B family, which is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Expression of the PSMB10 gene is induced by gamma interferon, and PSMB10 replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. Recombinant human PSMB10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Proteasome subunit beta type-10, LMP10, MECL1 |
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| Gene, Accession, CAS # | NP 002792 |
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| Catalog # | ATGP1212 |
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| Order / More Info | PSMB10, 40-273aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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