产品详情 |
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Antigenic Specificity | serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Maspin (SERPINB5) was discovered as a mammary tumor suppressor that is expressed in normal mammary epithelium but lost in most breast cancer cell lines . While maspin is related to the serpin family of serine protease inhibitors, it may not function as a protease inhibitor . It plays an essential role in embryonic development through critical roles in cell adhesion . While the precise mechanism of maspin signaling is unclear , the tumor suppressing activity of maspin has been attributed to its ability to inhibit cell invasion/metastasis and angiogenesis , while promoting apoptosis . Nuclear translocation of active IKKalpha has been shown to repress maspin transcription and promote prostate cancer metastasis . Synonyms: SERPINB5,PI5,maspin , |
Immunogen | Recombinant protein of human SERPINB5 |
Other Names | 1110036M19Rik|AI462524|AI646751|Maspin|PI-5|Spi7|ovalbumin|PI5|maspin|Pi5 |
Gene, Accession # | Gene ID: 5268,20724,116589 |
Catalog # | ABIN1683976 |
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Order / More Info | serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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