| 产品详情 |
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| Antigenic Specificity | serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) (aa 1-375) |
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| Clone | PAT2N6AT |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA,Western Blotting (WB),Immunofluorescence (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SERPINB5 (Maspin) is a tumor suppressor protein of the serine proteinase inhibitor family. Maspin plays a vital role in embryonic development through critical functions in cell adhesion. In addition, Maspin is present in normal breast and prostatic epithelial cells although down regulated in the particular carcinomas. SERPINB5 impedes the growth, invasion, and metastatic properties of mammary tumors as well as the invasive ability of pancreatic ductal adenocarcinoma cells. SERPINB5 being a breast tumor suppressor gene is a significant marker of the disease progression in breast neoplasms. Furthermore, high expression of maspin is linked to squamous cell carcinoma in non-small-cell lung cancer. Moreover, maspin expression has been directly linked with the biological aggressiveness of ovarian carcinoma. Maspin exhibits no serine protease inhibitory activity since it does not undergo the stressed to relaxed conformational transition typical of active serpinsSynonyms: PI5, maspin, SERPINB5, serpin peptidase inhibitor clade B (ovalbumin) member 5, Serpin B5, Protease inhibitor 5 |
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| Immunogen | Anti-human SERPINB5 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SERPINB5 AA 1-375 |
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| Other Names | 1110036M19Rik|AI462524|AI646751|Maspin|PI-5|Spi7|ovalbumin|PI5|maspin|Pi5 |
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| Gene, Accession # | Gene ID: 5268 |
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| Catalog # | ABIN808672 |
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| Order / More Info | serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) (aa 1-375) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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