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| Product Name | Recombinant Clostridium botulinum Botulinum neurotoxin type B |
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| Description | 1-427aa; Partial of Botulinum neurotoxin B light chain. MW: 51.34kD. Purity >90% as determined by SDS-PAGE. Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '76-Gln-|-Phe-77' bond of synaptobrevin-2. |
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| Size | 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (Baculovirus), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Bontoxilysin-B] |
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| Gene, Accession, CAS # | botB, Accession: P10844.3 |
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| Catalog # | MBS1107461 |
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| Order / More Info | Recombinant Clostridium botulinum Botulinum neurotoxin type B from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence.Whelan S.M., Elmore M.J., Bodsworth N.J., Brehm J.K., Atkinson T., Minton N.P.Appl. Environ. Microbiol. 58:2345-2354(1992) Szabo E.A., Pemberton J.M., Desmarchelier P.M. Gene probes for identification of the botulinal neurotoxin gene and specific identification of neurotoxin types B, E, and F.Campbell K.D., Collins M.D., East A.K.J. Clin. Microbiol. 31 |
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