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| Product Name | CNTF, Recombinant, Rat (Ciliary Neurotrophic Factor, HCNTF) |
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| Description | Purity ~99% (SDS-PAGE). CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. CNTF is a survival factor for various neuronal cell types and seems to prevent the degeneration of motor axons after axotomy. The CNTF is purified by proprietary chromatographic techniques. Source: Recombinant protein corresponding to rat CNTF, a single, non-glycosylated polypeptide chain containing 200aa, expressed in E. coli. Molecular Weight: ~22.834kD Biological Activity: Fully biologically active by its ability to phosphorylate STAT3 in several cel |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HCNTF, CNTF, Ciliary Neurotrophic Factor. |
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| Gene, Accession, CAS # | CNTF, Gene ID: 1270, SwissProt: P26441 |
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| Catalog # | 219662 |
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| Order / More Info | CNTF, Recombinant, Rat (Ciliary Neurotrophic Factor, HCNTF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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