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| Product Name | Herpesvirus 1 ICP47 Protein, Recombinant Human, aa1-88, His-Tag (US12) |
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| Description | Purity ~90% (SDS-PAGE). Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. pty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes. Source: Recombinant protein corresponding to aa1-88 from human Herpesvirus 1 ICP47 Protein, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~11.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Immediate-early protein IE12, Immediate-early-5 Infected cell protein 47, US12 protein Vmw12 |
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| Gene, Accession, CAS # | SwissProt: P03170 |
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| Catalog # | 373618 |
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| Order / More Info | Herpesvirus 1 ICP47 Protein, Recombinant Human, aa1-88, His-Tag (US12) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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