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Product Name | Mefloquine hydrochloride |
Description | Cx36 and Cx50 gap channel blocker (IC50 values are 0.3 and 1.1 μM, resepctively). Blocks gap junctional-coupling between interneurons in neocortical slices. Also antimalarial. Bind 80S ribosome of Plasmodium falciparum to inhibit protein synthesis. Improves survival in P berghei-infected mice. Additionally exhibits antischistosomal activity in vitro and in vivo. Purity 98%. MW (observed): 414.77 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (αS)-rel-α-(2R)-2-Piperidinyl-2,3-bis(trifluoromethyl-4-quinolinemethanol hydrochloride |
Gene, Accession, CAS # | CAS: 51773-92-3 |
Catalog # | 6819/50 |
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Order / More Info | Mefloquine hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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