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Product Name | AC 1903 |
Description | Selective TRPC5 blocker (IC50 = 13.6 μM). Also displays weak inhibition at TRPC4 (IC50 >100 μM) but not TRPC6. Exhibits no effect against a standard panel of profiling kinases. Blocks TRPC5 channel activity in glomeruli of proteinuric rats. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis (FSGS). Purity 98%. MW (observed): 303.36 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine |
Gene, Accession, CAS # | CAS: 831234-13-0 |
Catalog # | 6766/5 |
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Order / More Info | AC 1903 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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