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| Product Name | RNF212, Recombinant, Human, aa1-297, GST-Tag (RING Finger Protein 212) |
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| Description | Purity ~90% (SDS-PAGE). SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination Source: Recombinant protein corresponding to aa1-297 from human RNF212, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~60.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RING finger protein 212 |
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| Gene, Accession, CAS # | SwissProt: Q495C1 |
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| Catalog # | 375076 |
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| Order / More Info | RNF212, Recombinant, Human, aa1-297, GST-Tag (RING Finger Protein 212) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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