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| Product Name | RNF7, Recombinant, Human, aa2-113, His-Tag (RING-box Protein 2) |
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| Description | Purity ~85% (SDS-PAGE). Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents. Source: Recombinant protein corresponding to aa2-113 from human RNF7, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~14.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CKII beta-binding protein 1, CKBBP1RING finger protein 7 Regulator of cullins 2 Sensitive to apoptosis gene protein |
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| Gene, Accession, CAS # | SwissProt: Q9UBF6 |
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| Catalog # | 375079 |
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| Order / More Info | RNF7, Recombinant, Human, aa2-113, His-Tag (RING-box Protein 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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