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| Product Name | EGR1, Blocking Peptide (Zif268, Early Growth Response Protein 1, Krox-24, NGFI-A, TIS8, ZENK) |
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| Description | This peptide is used to block EGR1 rabbit poly #E2215-30 reactivity. EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (ER) to regulate target gene expression (1). The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1,2). Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2,3). Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry. Applications: Suitable for use as a blocking reagent to evaluate the specificity of antibody reactivity in immunohistochemistry protocols. Directions for Use: For immunohistochemistry, add twice the volume of peptide as volume of antibody used in 100ul total volume. Incubate for a minimum of 30 minutes prior to adding |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E2215-30A |
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| Order / More Info | EGR1, Blocking Peptide (Zif268, Early Growth Response Protein 1, Krox-24, NGFI-A, TIS8, ZENK) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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