| 产品详情 |
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| Product Name | Autocamtide-2 Peptide |
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| Description | Purity >95% by HPLC. Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the Thr-286 autophosphorylation site of the alpha subunit of CaMKII. Autocamtide-2 contains the R-X-X-S/T consensus site surrounded by basic residues for improved binding to phosphocellulose. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaMKII phosphorylates Autocamtide-2 with a Km of 2 uM whereas protein kinase C (PKC) has a Km > 50 uM and protein kinase A (PKA) has no activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Calcium/calmodulin-dependent protein kinase type II alpha chain, CaM-kinase II alpha chain, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H5040 |
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| Price | |
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| Order / More Info | Autocamtide-2 Peptide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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