产品详情 |
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Antigenic Specificity | Contactin 6 (CNTN6) (aa 930-980) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.Function:Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.Subcellular location: Cell membrane, Lipid-anchor, GPI-anchor.Tissue specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. Also known as: Neural recognition molecule NB-3, NB3,Contactin 6, CNTN6. |
Immunogen | A synthetic peptide from aa region 930-980 of human Contactin 6 conjugated to an immunogenic carrier protein was used as the antigen. |
Other Names | NB-3|DKFZp459A015|NB3 |
Gene, Accession # | Gene ID: 27255,53870,27256 |
Catalog # | ABIN350255 |
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Order / More Info | Contactin 6 (CNTN6) (aa 930-980) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 9486763, 16959974 |
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