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| Product Name | C1 Inhibitor, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). C1 Inhibitor is a member of the serpin family of structurally related proteins, and is the primary regulator of the immune complement system. C1 Inhibitor is a protease inhibitor that functions to inhibit the complement system in order to prevent over-activation or spontaneous activation. Inhibition is achieved by binding to and irreversibly inhibiting the C1r and C1s proteases of the C1 complex, which has the effect of shutting down all subsequent downstream events in the complement activation cascade. C1inhibitor can also inhibit various other proteases, including Kallikrein, Factor XIa, and Factor XIIa. Deficiencies in C1inhibitor are the primary cause of hereditary angioedema (HAE, hereditary angioneurotic edema), a disease characterized by edema in the respiratory and gastrointestinal tracts. In certain clinical situations, the direct administration of C1inhibitor can be used to treat HAE and certain other conditions. Recombinant Human C1 Inhibitor is a hig |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | C1 Inhibitor, Recombinant, Human (SERPING1, Plasma Protease C1 Inhibitor, C1inh, C1 Esterase Protein, C1-inhibiting Factor, Serpin G1) |
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| Gene, Accession, CAS # | SERPING1, Gene ID: 710, SwissProt: P05155 |
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| Catalog # | 219511 |
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| Order / More Info | C1 Inhibitor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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