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| Product Name | C1 Inhibitor, Recombinant, Human |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. C1Inhibitor is a member of the serpin family of structurally related proteins, and is the primary regulator of the immune complement system. C1 Inhibitor is a protease inhibitor that functions to inhibit the complement system in order to prevent over-activation or spontaneous activation. Inhibition is achieved by binding to and irreversibly inhibiting the C1r and C1s proteases of the C1 complex, which has the effect of shutting down all subsequent downstream events in the complement activation cascade. C1 inhibitor can also inhibit various other proteases, including Kallikrein, Factor XIa, and Factor XIIa. Deficiencies in C1 inhibitor are the primary cause of hereditary angioedema (HAE, hereditary angioneurotic edema), a disease characterized by edema in the respiratory and gastrointestinal tracts. In certain clinical situations, the direct administration of C1 inhibitor can be used to treat HAE and certain other conditions. Recombinant Hu |
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| Size | 50ug, 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | C1 Inhibitor, Recombinant, Human (Plasma Protease C1 Inhibitor, C1 Inh, C1Inh, C1 Esterase Inhibitor, C1-inhibiting Factor, Serpin G1, C1IN, C1NH) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143299 |
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| Order / More Info | C1 Inhibitor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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