产品详情 |
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Antigenic Specificity | PI3 Kinase P85 alpha (aa 600-650) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphoinositide 3-kinase (PI3K) catalyzes the phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2). PI3Ks are composed of a catalytic subunit (p110) and a regulatory subunit (p85). The catalytic subunits of PI3K include p110 alpha, p110 beta, p110 gamma, and p110 delta, while the regulatory subunits contain p85 alpha and p85 beta. p85 alpha regulates the catalytic activity of p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain. The p85 alpha has been implicated in insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. |
Immunogen | KLH-coupled synthetic peptide within residues 600-650 of human PI3 Kinase p85 alpha |
Other Names | AA414921|C530050K14|PI3K|p50alpha|p55alpha|p85alpha|AGM7|GRB1|p85|p85-ALPHA|PI3KA |
Gene, Accession # | Gene ID: 5295 |
Catalog # | ABIN2017599 |
Price | |
Order / More Info | PI3 Kinase P85 alpha (aa 600-650) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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