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| Product Name | Recombinant Human Retinoblastoma-associated protein (RB1) , partial |
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| Description | MW: 106,159 Da. Purity >85% (SDS-PAGE). This protein is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
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| Size | 0.5 mg (E-Coli), 0.05 mg (Baculovirus), 0.5 mg (Yeast), 0.05 mg (Mammalian-Cell), 1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [retinoblastoma-associated protein; Retinoblastoma-associated protein; retinoblastoma-associated protein; RB transcriptional corepressor 1; p105-Rb; pRb; Rb; pp110] |
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| Gene, Accession, CAS # | RB1, Gene ID: 5925, Accession: NP_000312.2 |
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| Catalog # | MBS718064 |
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| Price | |
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| Order / More Info | Recombinant Human Retinoblastoma-associated protein (RB1) , partial from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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