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| Product Name | Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 (mcr1) |
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| Description | 1-541aa; Full Length. MW: 76.1 kDa. Purity ≥90%. Probably catalyzes the addition of a phosphoethanolamine moiety to lipid A. Phosphoethanolamine modification of lipid A gives polymyxin resistance (PubMed:26603172).1 PublicationConfers resistance to polymyxin-type antibiotics; expression of the Mcr-1 protein in E.coli increases colistin and polymyxin B minimal inhibitory concentration (MIC) from 0.5 mg/ml to 2.0 mg/ml. The pHNSHP45 plasmid can transfer efficiently (0.1 to 0.001) to other E |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Polymyxin resistance protein MCR-1] |
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| Gene, Accession, CAS # | [mcr1] |
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| Catalog # | MBS7088041 |
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| Order / More Info | Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 (mcr1) from MYBIOSOURCE INC. |
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| Product Specific References | Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.Liu Y.Y., Wang Y., Walsh T.R., Yi L.X., Zhang R., Spencer J., Doi Y., Tian G., Dong B., Huang X., Yu L.F., Gu D., Ren H., Chen X., Lv L., He D., Zhou H., Liang Z., Liu J.H., Shen J.Lancet Infect. Dis. 16:161-168(2016) |
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