| 产品详情 |
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| Product Name | RAB31, Recombinant, Human, aa1-194, GST-Tag (Ras-related Protein Rab-31) |
| Description | Purity ~90% (SDS-PAGE). The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Source: Recombinant protein corresponding to aa1-194 from human RAB31, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~48.6kD AA |
| Size | 10ug, 50ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Ras-related protein Rab-22B |
| Gene, Accession, CAS # | SwissProt: Q13636 |
| Catalog # | 374970 |
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| Order / More Info | RAB31, Recombinant, Human, aa1-194, GST-Tag (Ras-related Protein Rab-31) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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