| 产品详情 |
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| Product Name | Recombinant Human Cytochrome b-245 heavy chain |
| Description | 283-570aa; Partial. MW: 49.21kD. Purity >90% as determined by SDS-PAGE. Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked b |
| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1gp91-phoxp22 phagocyte B-cytochrome] |
| Gene, Accession, CAS # | CYBB, Gene ID: 1536, Accession: NP_000388.2 |
| Catalog # | MBS963114 |
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| Order / More Info | Recombinant Human Cytochrome b-245 heavy chain from MYBIOSOURCE INC. |
| Product Specific References | Cloning the gene for an inherited human disorder -- chronic granulomatous disease -- on the basis of its chromosomal location.Royer-Pokora B., Kunkel L.M., Monaco A.P., Goff S.C., Newburger P.E., Baehner R.L., Cole F.S., Curnutte J.T., Orkin S.H.Nature 322:32-38(1986) CYBB mutation analysis in X-linked chronic granulomatous disease.Jirapongsananuruk O., Niemela J.E., Malech H.L., Fleisher T.A.Clin. Immunol. 104:73-76(2002) NHLBI resequencing and genotyping service (RS&G)Complete sequencing and c |
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