| 产品详情 |
| Edit |   |
|---|
| Product Name | Wedelolactone |
|---|
| Description | Purity >98%. Wedelolactone is a natural coumestan originally isolated from plants used in herbal therapies. It inhibits NF-?B signaling at the level of IKK action, resulting in suppression of NF-?B-mediated gene expression at concentrations of 1-100 µM. Wedelolactone can also inhibit hepatitis C virus NS5B RNA-dependent RNA polymerase in vitro (IC50 = 36 µM), STAT1 dephosphorylation (50 µM), and EZH2-EED interactions (Kd = 2.8 µM). Prolonged incubation of HepG2 liver cells with wedelolactone alters lipid metabolism through increased expression of AMPK, PPARAlpha, lipoprotein lipase, and low-density lipoprotein receptor. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 1,8,9-trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one, IKK Inhibitor II |
|---|
| Gene, Accession, CAS # | CAS: 524-12-9 |
|---|
| Catalog # | LS-H10486 |
|---|
| Price | |
|---|
| Order / More Info | Wedelolactone from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|