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Product Name | Complement Alternative pathway ELISA |
Description | The Eagle Biosciences Complement Alternative Pathway ELISA Assay Kit combines principles of the hemolytic assay for complement activation with the use of labelled antibodies specific for neoAntigens produced as a result of complement activation. The amount of neoAntigens generated is proportional to the functional activity of complement pathways. Sample Types: serum. Range: Cut-off. Sensitivity: Cut-off. Time: 2 hours • In vitro activation of the complement sequence leads to the consumption of complement components which, in turn, leads to a decrease in their concentration. Thus, the determination of complement proteins or complement activity is used to indicate whether the complement system has been activated by an immunologic and/or pathogenic mechanism. Both functional and immunochemical complement measurements are used to evaluate subjects when a complement-activating disease is suspected or an inherited deficiency is possible. The level of complement activity evaluated by functional assays such as Eagle Biosciences Complement Alternative Pathway ELISA Assay Kit takes into account the rate of synthesis, degradation, and consumption of the components and provides a measure of the integrity of the pathways as opposed to immunochemical methods which specifically measure the concentration of various complement components. |
Size | 1 x 96 well |
Concentration | n/a |
Applications | RUO |
Other Names | Complement Alternative pathway ELISA |
Gene, Accession, CAS # | n/a |
Catalog # | COMPL AP330 |
Price | |
Order / More Info | Complement Alternative pathway ELISA from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |
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