| 产品详情 |
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| Product Name | DHEA ELISA |
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| Description | In the DHEA ELISA Assay Kit, the essential reagents required for this immunoenzymatic assay are a biotinylated anti DHEA antibody, the DHEA Antigens conjugated with the enzyme HRP (horseradish peroxidase), the DHEA Antigens present in the sample, and a microplate coated with Streptavidin (highly specific for Biotin). The quantity of native Antigens is unknown, while the antibody and the Antigens linked to HRP are in excess. In the first part of the DHEA ELISA Assay Kit these three components are mixed together; a competitive reaction for the anti DHEA antibody between the native Antigens and the Antigens linked to HRP develops. Sample Types: serum, plasma. Range: 0.5 - 30 ng/ml. Sensitivity: 10 ng/ml. Time: 1.5 hours • Some studies showed a decrease in the DHEA production in women with risk for the breast cancer. In animal models DHEA showed a role in the therapeutic action against diabetes, obesity and cardiovascular pathologies, and unclear roles in immunology, in lipid metabolism (also cholesterol) and in the nervous system. Seric levels of DHEA are relatively high in fetal and neonatal age, decrease during childhood and increase again during puberty until 30 years. No DHEA variations have been observed during pregnancy or menstrual cycle. Seric levels of DHEA are 100-1000 times lower than the levels of DHEA sulphate (DHEA-S). The measurement of seric levels of DHEA is a marker for adrenal androgen synthesis. Abnormal low levels of DHEA can be observed in the hypoadrenalism, while elevated levels can be observed in various pathologies such as the surrenalic adenomas, 21-hydroxylase and 3b-hydroxysteroid dehydrogenase deficiency and in some cases of female hirsutism. |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | DHEA-S,Dehydroepiandrosterone sulfate,adrenal androgen synthesis |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | DCM124 |
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| Order / More Info | DHEA ELISA from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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