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| Product Name | TNF Receptor-Associated Protein 1, Recombinant, Human, FLAG-tag |
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| Description | Purity ~95% (SDS-PAGE). Human TRAP1 belongs to the mitochondrial heat shock protein family. These molecular chaperones are highly conserved and play an important role in signal transduction, protein folding and degradation. Recombinant human TRAP1 has a C-terminal FLAG tag and has 702aa residues. It has been identified to be protective for cell survival, and has been suggested as a target for anti-cancer therapeutics. Also can be useful for studies including enzyme kinetics, activator screening and selectivity profiling. Source: Recombinant protein corresponding to 702aa residues from human TNF Receptor-Associated Protein 1, fused to FLAG-tag at C-terminal, expressed in E. coli. Molecular Weight: ~76.5kD Biological Activity: Kd=1.95nM Assay Conditons: 20mM HEPES, pH 7.5, 50mM KCl, 5mM MgCl2, 20mM sodium molybdate, 2mM DTT, 0.01% NP40, 100ug/ml BSA, 50nM TRAP1, geldanamycin-FITC (titration range 0.016-16nM) incubated at 4°C for 24 hrs. Fluorescence polarization measured at RT (Ex/Em= 48 |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNF Receptor-Associated Protein 1, Recombinant, Human, FLAG-tag (TRAP1, Heat Shock Protein 75kD, HSP 75, TNFR-associated Protein 1, Tumor Necrosis Factor type 1 Receptor-associated Protein, TRAP-1) |
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| Gene, Accession, CAS # | TRAP1, Gene ID: 10131, SwissProt: Q12931 |
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| Catalog # | 220337 |
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| Order / More Info | TNF Receptor-Associated Protein 1, Recombinant, Human, FLAG-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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