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| Product Name | TNF, Recombinant, Sheep, aa78-234, GST-Tag (Tumor Necrosis Factor) |
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| Description | Purity ~90% (SDS-PAGE). Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells. Source: Recombinant protein corresponding to aa78-234 from sheep TNF, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~44.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cachectin,TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a |
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| Gene, Accession, CAS # | SwissProt: P23383 |
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| Catalog # | 375617 |
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| Order / More Info | TNF, Recombinant, Sheep, aa78-234, GST-Tag (Tumor Necrosis Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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