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| Product Name | NMNAT3, Recombinant, Human, aa1-252, His-tag |
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| Description | Purity ~95% (SDS-PAGE). This is the Mitochondrial NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It can use tiazofurin monophosphate as substrate. It can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. It fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. It protects against axonal degeneration following injury. Source: Recombinant protein corresponding to aa1-252 of human NMNAT3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~27kD Biological Activity: ≥2U/mg protein Unit Definition: One unit is defined as the amount of enzyme t |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NMNAT3, Recombinant, Human, aa1-252, His-Tag (Nicotinamide Mononucleotide Adenylyl-Transferase 3, NMN AdenylylTransferase 3, NaMN AdenylylTransferase 3) |
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| Gene, Accession, CAS # | NMNAT3, Gene ID: 349565, SwissProt: Q96T66 |
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| Catalog # | 301257 |
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| Order / More Info | NMNAT3, Recombinant, Human, aa1-252, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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