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| Product Name | NMNAT2, Recombinant, Human, aa1-307, His-Tag (Nicotinamide Mononucleotide Adenylyltransferase 2) |
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| Description | Purity ~85% (SDS-PAGE). NMNAT2 belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. Source: Recombinant protein corresponding to aa1-307 from human NMNAT2, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~36.6kD (327aa) Specific Activity: ~500pmol/min/ug Unit Definition: One unit will convert 1.0pmole of beta-NADH/minute to beta-NAD at pH 8.0 at 37°C. Activity Assay: 1. Prepare a 200ul reaction buffer into a suitable container: The final concentrations are 20mM Tris-HCl, pH 8.0, 10mM MgCl2, 1mM ATP, 1% ethanol, 1mM beta-NMN, 100mM sodium chloride, 6 unit ADH. 2. Equilibrate to 37°C and monitor at |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_055854 |
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| Catalog # | 218398 |
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| Order / More Info | NMNAT2, Recombinant, Human, aa1-307, His-Tag (Nicotinamide Mononucleotide Adenylyltransferase 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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