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| Product Name | Interleukin-27/p28 |
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| Description | Purity ~97% (SDS-PAGE, HPLC). The p28 subunit of IL-27 (IL-27/p28), also known as Interleukin-30 (IL-30), is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), p28 forms a heterodimer known as IL-27. p28 is thought to be a pro-inflammatory cytokine inducing immuno-modulatory effects, but the details of these effects are currently unclear and research is focused on delineating its specific biological functions. Source: Recombinant protein corresponding to mouse Interleukin-27/p28, a non-glycosylated protein containing 207aa, expressed in E. coli. Molecular Weight: ~23.7kD Biological Activity: Measured by dose-dependent inhibition of TGF-beta and Il-6-induced IL-17A expression in mouse CD4 splenocytes. 50ng/ml of mouse p28 is capable of inhibiting ≥25% of Il-17A expression in this assay. Endotoxin: <0.1ng/ug |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Interleukin-27/p28 (IL-27), Recombinant, Mouse (IL27, Interleukin 27, IL 27, Interleukin 27, IL-30, Interleukin 30) |
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| Gene, Accession, CAS # | IL27, Gene ID: 246779, SwissProt: Q8K3I6 |
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| Catalog # | 219978 |
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| Order / More Info | Interleukin-27/p28 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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