| 产品详情 |
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| Product Name | PF-03814735 |
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| Description | MW: 474.48. Purity ≥98% by HPLC. PF-03814735 is an ATP-competitive inhibitor of Aurora kinases A and B with IC50 values of 0.8 and 0.5 nM respectively. It has shown to block cytokinesis; inhibit cellular proliferation in many tumor cell lines including HCT-116; HL-60 and A549. In vitro experiments have shown that PF 03814735 inhibits the phosphorylation of Aurora B H3 and Aurora A cultured MDA-MB-231 cells. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [N-[2-[ (1S; 4R)-6-[[4- (Cyclobutylamino)-5- (trifluoromethyl)-2-pyrimidinyl]amino]-1; 2; 3; 4-tetrahydronaphthalen-1; 4-imin-9-yl]-2-oxoethyl]-acetamide] |
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| Gene, Accession, CAS # | CAS: 942487-16-3 |
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| Catalog # | MBS846399 |
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| Price | |
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| Order / More Info | PF-03814735 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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