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| Antigenic Specificity | FEN1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:10 - 1:100; IP1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-FEN1 polyclonal antibody. The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both bindi |
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| Immunogen | flap structure-specific endonuclease 1 |
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| Other Names | RAD2 |
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| Gene, Accession # | Gene ID: 2237, UniProt: P39748 |
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| Catalog # | FNab03075 |
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| Price | |
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| Order / More Info | FEN1 Antibody from FINETEST |
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| Product Specific References | n/a |
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