| 产品详情 |
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| Antigenic Specificity | FIP1L1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IF • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-FIP1L1 polyclonal antibody. This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. |
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| Immunogen | FIP1 like 1 (S. cerevisiae) |
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| Other Names | FIP1, RHE |
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| Gene, Accession # | Gene ID: 81608, UniProt: Q6UN15 |
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| Catalog # | FNab03131 |
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| Price | |
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| Order / More Info | FIP1L1 Antibody from FINETEST |
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| Product Specific References | n/a |
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| 产品资料 |
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